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Table 2 Spirometry parameters

From: Comparison of two porcine acute lung injury models: a post-hoc analysis

Parameter

Group

BLH

T0

T4

T8

Mean (SD)

Mean (SD)

Mean (SD)

Mean (SD)

PaO2/FiO2

Double-Hit

367 (64)

76 (35)#/*

225 (54)*

212 (79)*

[mmHg]

LPS

509 (41)

470 (51)

238 (57)*

144 (59)*

FRC

Double-Hit

535 (54)

222 (79)

373 (63)

375 (60)

[ml]

LPS

779 (490)

688 (488)

402 (88)

363 (165)

Ppeak

Double-Hit

16 (0)

28 (4)#/*

25 (4)*

24 (4)*

[mbar]

LPS

15 (2)

17 (2)*

26 (5)*

28 (5)*

Pmean

Double-Hit

8 (0)

14 (2)#/*

14 (3)*

12 (3)*

[mbar]

LPS

8 (1)

9 (1)

12 (2)*

14 (3)*

PEEP

Double-Hit

4 (0)

5 (1)

8 (3)#/*

7 (2)*

[cm H2O]

LPS

4 (0)

5 (0)

6 (2)

8 (2)*

MV

Double-Hit

7.36 (1.15)

7.87 (1.02)#

8.85 (1.50)#/*

9.11 (1.37)#/*

[l min−1]

LPS

6.48 (0.58)

6.56 (0.53)

7.55 (0.97)*

7.58 (0.96)*

RR

Double-Hit

37 (4)

38 (4)#

45 (5)#/*

46 (5)#/*

[min−1]

LPS

32 (4)

30 (5)

33 (5)

35 (6)

Compliance

Double-Hit

17.08 (1.78)

8.80 (2.16)#/*

11.39 (2.79)*

10.88 (2.30)*

[ml/mbar]

LPS

24.94 (4.60)

20.31 (3.69)*

13.15 (2.22)*

12.87 (1.84)*

  1. *Indicates p < 0.05 vs. baseline value. # indicates p < 0.05 in intergroup comparison
  2. PaO2: arterial oxygen; FiO2: fraction of inspired oxygen; PaO2/FiO2: oxygen index; FRC: functional residual capacity; MV: minute ventilation; Ppeak: peak inspiratory pressure; Pmean: mean airway pressure; PEEP: positive end-expiratory pressure; RR: respiratory rate