Fig. 2

Comparison of Lactate (A) and XL (B) between the control group (CG) and the shock group (SG). Comparison of the SG for paired data for maximum lactate values per subject per event (Lac_Max) (C), and minimum XL values per subject per event (XL_Min) (D). Events by shock criterion (MAP ≤ 48 mmHg) T-2: 2 h before shock; T-1: 1 h before shock; T0: shock; T1: 1 h after shock; T2: 2 h after shock. Significant differences between groups are marked as bars with their corresponding p values. Post hoc Dunn's all-pairs test for Kruskal–Wallis rank-sum test and post hoc Durbin's all-pairs test for Friedman rank-sum test. Significant p values < 0.05. Full Post hoc analysis per variable and time point is available in Additional file 5: Tables S4–S7