Table 3 Respiratory mechanics
Parameter | Group | T0 | T1 | T2 | T3 | Group effect | Time effect | Group vs. time effect |
|---|---|---|---|---|---|---|---|---|
VT (mL/kg) |  |  |  |  | p = 0.246 | p = 0.132 | p = 0.174 | |
NORMO | DEX | 6.67 (5.91–7.12) | 6.67 (6.21–7.12) | 6.90 (6.55–7.97) | 6.67 (6.19–7.59) |  | ||
HYPO | 7.35 (7.04–7.94) | 7.73 (7.10–8.65) | 7.48 (7.10–8.47) | 7.94 (7.59–8.62) | ||||
NORMO | PRO | 6.84 (6.39–7.76) | 6.76 (6.32–7.77) | 7.00 (6.62–7.83) | 7.13 (6.60–7.88) | |||
HYPO | 7.73 (6.31–9.46) | 7.51 (6.31–8.14) | 8.34 (7.29–9.14) | 7.50 (7.05–7.69) | ||||
Pplat, RS (cmH2O) |  |  |  |  | p = 0.003 | p = 0.020 | p = 0.961 | |
NORMO | DEX | 14.10 (11.45–15.65) | 14.20 (11.40–15.55) | 16.10 (1.93–16.30) | 14.80 (12.45–16.80) | T0 HYPO-PRO vs NORMO-PRO, p = 0.026 T1 HYPO-PRO vs NORMO-PRO, p = 0.008 | ||
HYPO | 14.30 (12.90–16.72) | 16.15 (14.39–16.73) | 15.90 (13.55–17.10) | 16.45 (15.23–16.80) | ||||
NORMO | PRO | 9.25 (8.80–11.19) | 11.03 (8.65–11.93) | 11.50 (9.90–12.05) | 11.10 (9.28–13.30) | |||
HYPO | 13.84 (12.20–15.43) | 15.24 (13.10–16.80) | 14.55 (13.05–16.30) | 14.40 (11.70–16.80) | ||||
ΔP, RS (cmH2O) |  |  |  |  | p = 0.017 | p < 0.001 | p = 0.476 | |
NORMO | DEX | 11.00 (8.00–12.10) | 10.50 (8.80–12.00) | 12.80 (9.18–13.30) | 11.50 (9.90–14.40) |  | ||
HYPO | 10.75 (9.20–12.93) | 12.68 (11.35–13.08) | 12.55 (9.85–14.51) | 12.70 (11.50–16.76) | ||||
NORMO | PRO | 6.25 (5.78–7.59) | 8.08 (6.03–9.03) | 9.15 (8.38–9.65) | 9.45 (8.95–10.78) | |||
HYPO | 9.99 (8.63–12.45) | 11.44 (9.53–13.22) | 10.87 (9.41–13.29) | 10.65 (8.38–13.23) | ||||