Parameter | Group | T0 | T1 | T3 | Group effect | Time effect | Group vs. time effect | |
---|---|---|---|---|---|---|---|---|
pHa | NORMO | DEX | 7.54 (7.51–7.57) | 7.47 (7.40–7.49) | 7.43 (7.40–7.45) | p = 0.408 | p < 0.001 | p = 0.036 |
HYPO | 7.50 (7.46–7.55) | 7.47 (7.38–7.49) | 7.41 (7.27–7.46) | |||||
NORMO | PRO | 7.46 (7.40–7.52) | 7.46 (7.36–7.49) | 7.41 (7.35–7.50) | ||||
HYPO | 7.51 (7.47–7.53) | 7.49 (7.44–7.54) | 7.46 (7.39–7.48) | |||||
PaO2/FiO2 | NORMO | DEX | 237.50 (168.60–488.00) | 381.30 (275.00–446.90) | 317.50 (192.50–445.60) | p = 0.808 | p = 0.144 | p = 0.893 |
HYPO | 301.30 (171.30–401.90) | 428.80 (261.30–461.30) | 423.80 (224.40–461.30) | |||||
NORMO | PRO | 303.50 (177.50–438.10) | 385.00 (335.00–445.50) | 403.80 (384.40–451.30) | ||||
HYPO | 397.50 (190.00–473.10) | 406.30 (203.80–489.90) | 381.3 (187.50–450.00) | |||||
PaCO2 (mmHg) | NORMO | DEX | 30.35 (26.40–35.48) | 31.45 (29.68–36.18) | 29.80 (28.35–31.55) | p = 0.118 | p = 0.383 | p = 0.108 |
HYPO | 34.75 (32.05–38.13) | 37.45 (29.10–52.00) | 38.85 (33.05–47.93) | |||||
NORMO | PRO | 38.25 (32.55–41.60) | 32.15 (29.35–40.70) | 36.80 (27.33–48.95) | ||||
HYPO | 34.65 (31.95–36.63) | 27.60 (26.70–33.10) | 36.85 (28.80–39.53) | |||||
HCO3− (mEq/L) | NORMO | DEX | 24.80 (22.78–30.23) | 23.00 (21.05–24.23) | 18.80 (18.13–20.98) | p = 0.418 | p < 0.001 | p = 0.181 |
HYPO | 26.50 (24.98–28.48) | 25.60 (22.38–30.53) | 23.40 (18.15–26.15) | |||||
NORMO | PRO | 24.35 (23.23–28.98) | 22.35 (20.18–24.68) | 23.75 (19.03–26.03) | ||||
HYPO | 27.40 (23.48–30.13) | 22.35 (21.25–24.75) | 23.30 (21.85–25.35) |