A novel method to calculate compliance and airway resistance in ventilated patients

Intensive Care Medicine Experimental

Table 1 Respiratory system’s static compliance and resistance values calculated by the static and dynamic methods using a test lung

V_tidal	PEEP*	Compliance mL·cmH₂O ⁻¹		Resistance cmH₂O·s·L⁻¹
mL	cmH₂O	Static	Dynamic	Static	Dynamic
	0	21.0[21.0,21.0]	21.5[21.4,21.5]	7.9[7.9,8.0]	7.7[7.6,7.8]
300	5	22.8[22.8,22.9]	23.2[23.1,23.3]	8.2[5.2,8.3]	8.3[8.2,8.3]
	10	26.1[26.0,26.1]	26.4[26.4,26.3]	8.2[7.9,8.2]	8.1[8.1,8.3]
	0	22.9[22.9,23.0]	23.0[23.0,23.1]	10.5[10.4,10.5]	10.1[10.0,10.1]
400	5	24.4[24.4,24.5]	24.7[24.6,24.8]	10.7[10.7,10.8]	11.0[11.0,11.0]
	10	27.7[27.7,27.8]	28.1[28.0,28.1]	10.7[10.7,11.1]	11.0[10.9,11.0]
Total (n = 880)		23.6[22.8,26.1]	23.9[23.0,26.4]	9.3[8.2,10.7]	9.2[8.1,10.9]
Difference^†		0.3 [0.2,0.4]		0 [− 0.2,0.2]

There were no significant differences between methods in any of the variables measured
V_tidal tidal volume, PEEP positive end expiratory pressure; values shown as median [IQR]
^*Five epochs per PEEP level, each containing approximately 30 breaths
^†Difference = dynamic – static methods