Table 3 Regression analysis for primary and secondary outcomes from symptom day 15 onwards

Primary outcome

 PaO₂/FiO₂ Ratio (mmHg)

– 0.377 (0.111)

p < 0.03

Secondary outcomes

 Mortality

  Death at 60 days from symptom onset (crude mortality)

1.41 (1.1–2.0)

p < 0.03

  Death at 60 days from symptom onset (hypoxaemic respiratory failure)^✸

1.90 (1.3–3.1)

p < 0.01

 Organ-support dependency

  Any organ support^✦

1.66 (1.1–2.9)

p < 0.05

  Artificial mechanical ventilation only

1.66 (1.00–2.9)

p = 0.05

  Per additional organ supported^✦

50.72 (23.0)

p < 0.05

  Per additional organ supported (hypoxaemic respiratory failure)^✦✸

63.67 (23.3)

p < 0.01

 Biochemical inflammatory markers

  C-reactive protein (CRP)

0.065 (0.29)

p > 0.5

  Lymphocyte (as % of white blood cells)

− 118.4 (109)

p > 0.2

  Neutrophil/lymphocyte ratio

2.67 (1.3)

p = 0.05

  Neutrophil/lymphocyte ratio (hypoxaemic respiratory failure)^✸

3.54 (1.4)

p < 0.03