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Table 1 Mechanical ventilation data and hemodynamic parameters taken at baseline, PEEP 10, PEEP 15, PEEP 20 and at release of PEEP

From: Releasing high positive end-expiratory pressure to a low level generates a pronounced increase in particle flow from the airways

 

Baseline

PEEP 10

PEEP 15

PEEP 20

RELEASE

Mechanical ventilation

     

 Volume/minute (liter)

8 (7.8–8)

8 (7.8–8)

8 (7.8–8)

8 (7.8–8)

8 (7.8–8)

 Peak pressure (cmH2O)

13.7 (13.3–14.2)

19.9 (19–20)

24.6 (21.5–26.2)

31 (28.9–32.3) 0.03

12.4 (12–13.2)

 Mean pressure (cmH2O)

7.2 (7.1–7.4)

12 (11.9–12.6)

17.1 (14.7–17.9)

22.2 (22–23.7) 0.02

7 (6.6–7.1)

Hemodynamics

     

 Pulse (beats per minute)

70 (45–104)

78 (53–102)

77 (63–115)

84 (63–94)

57 (51–94)

 Systolic BP (mmHg)

120 (92–135)

88 (73–140)

95 (78–118)

80 (53–92) 0.01

77 (68–172)

 Diastolic BP (mmHg)

72 (59–72)

50 (37–92)

45 (41–64)

27 (26–50)

42 (37–97)

 Mean BP (mmHg)

92 (70–98)

63 (49–108)

64 (54–80)

45 (35–64) 0.01

45 (45–107)

 Saturation (%)

98 (98–100)

99 (97–100)

99 (97–100)

97 (95–100)

99 (96–100)