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Table 1 Hemodynamics during partial resuscitative endovascular balloon occlusion of the aorta

From: A randomized porcine study of hemorrhagic shock comparing end-tidal carbon dioxide targeted and proximal systolic blood pressure targeted partial resuscitative endovascular balloon occlusion of the aorta in the mitigation of metabolic injury

 

Baseline

Hemorrhage

15 min pREBOA

30 min pREBOA

45 min pREBOA

15 min reperfusion

60 min reperfusion

120 min reperfusion

180 min reperfusion

HR (beats min−1)

 pREBOAETCO2

117 (101–132)

163 (137–189)

175 (145–204)

192 (153–220)

181 (158–204)

173 (156–191)

165 (148–183)

143 (125–162)

140 (116–165)

 pREBOASBP

127 (107–148)

206 (192–220)

198 (176–220)

211 (197–225)

199 (184–214)

160 (152–168)

169 (158–181)

161 (140–183)

156 (132–179)

MAP (mm Hg)

 pREBOAETCO2

92 (85–100)

35 (30–40)

71 (58–84)

73 (57–89)

69 (51–87)

61 (46–75)

72 (60–85)

71 (59–82)

69 (58–81)

 pREBOASBP

94 (86–103)

34 (29–38)

66 (60–72)

58 (48–69)

62 (55–70)

44 (40–48)

59 (54–64)

59 (50–64)

58 (47–69)

CVP (mm Hg)

 pREBOAETCO2

7 (6–8)

4 (3–5)

5 (4–6)

5 (4–6)

5 (4–6)

7 (6–8)

7 (6–8)

6 (6–7)

7 (6–8)

 pREBOASBP

9 (8–10)

5 (4–6)

7 (6–8)

7 (6–8)

7 (6–8)

9 (8–10)

9 (8–9)

8 (7–9)

8 (7–8)

CO (l min−1)

 pREBOAETCO2

6.1 (5.5–6.7)

2.8 (2.4–3.2)

3.0 (2.3–3.6)

3.3 (2.5–4.0)

3.2 (2.5–4.0)

4.8 (3.8–5.8)

6.0 (5.4–6.7)

5.2 (4.7–5.7)

4.6 (4.1–5.0)

 pREBOASBP

5.2 (4.5–5.6)

2.4 (2.2–2.6)

2.8 (2.5–3.1)

2.87 (2.5–3.2)

2.9 (2.5–3.3)

4.0 (3.4–4.5)

5.8 (5.2–6.5)

4.47 (3.8–5.1)

4.0 (3.2–4.5)

  1. Hemodynamics during end-tidal carbon dioxide (ETCO2) targeted partial resuscitative endovascular balloon occlusion of the aorta (pREBOA, pREBOAETCO2, n = 10) and proximal systolic blood pressure targeted pREBOA (pREBOASBP, n = 10) in anesthetized, mechanically ventilated pigs. Data are means (95% confidence intervals)
  2. HR: heart rate; MAP: mean arterial pressure; CVP: central venous pressure; CO: cardiac output