Fig. 2
From: Insulin signaling in skeletal muscle during inflammation and/or immobilisation
Methaemoglobin (MetHb) blood levels in %. The control (mean [SD]; day 0: 0.29 [0.06], day 4: 0.31 [0.16], day 8: 0.26 [0.09], day 12: 0.30 [0.00]; p = 0.380) and immobilisation (mean [SD]; day 0: 0.26 [0.08], day 4: 0.25 [0.09], day 8: 0.25 [0.16], day 12: 0.30 [0.02]; p = 0.293) group showed no change in methaemoglobin blood levels over time while in the inflammation (mean [SD]; day 0: 0.28 [0.08], day 4: 2.65 [2.31], day 8: 7.07 [5.73], day 12: 6.50 [5.09]; p < 0.001) as well as immobilisation and inflammation (mean [SD]; day 0: 0.28 [0.05], day 4: 6.22 [5.57], day 8: 4.77 [4.62], day 12: 8.06 [4.75]; p < 0.001) groups a significant increase over time was present. This led to significantly increased values in the inflammation group in comparison with the control and immobilisation group on day 4 (p = 0.035/p = 0.027) as well as on day 8 (p < 0.001 for both groups) and 12 (p < 0.001 for both groups). The immobilisation and inflammation group showed an increase over all three other groups on day 4 (p < 0.001 for all three groups) and over the control and immobilisation groups on day 8 (p < 0.001 for both groups) and 12 (p < 0.001 for both groups). The scale of the y-axis has been Log2 transformed. The number of identical symbols at the top of the error bars indicate the significance level: one < 0.05; two < 0.01 and three < 0.001. *showed significant difference over time with the colour of the symbol indicating the respective group. # showed significant difference to the control group at the specific time point. +Significant difference to the immobilisation group at the specific time point. § showed significant difference to the inflammation group at the specific time