Table 3 Physiological parameters and laboratory results for Pig 18–Pig 24 and control
Baseline | 3 h | 6 h | 9 h | 12 h | 15 h | 18 h | 21 h | 24 h | 27 h | 30 h | |
|---|---|---|---|---|---|---|---|---|---|---|---|
HR ± SD (beats × min−1) | 98 ± 33 | 100 ± 26 | 113 ± 36 | 103 ± 52 | 100 ± 36 | 98 ± 25 | 98 ± 25 | 106 ± 31 | 110 ± 21 | 128 ± 23 | 123 ± 31 |
Control | 108 | 101 | 100 | 88 | 85 | 83 | 81 | 93 | 87 | 68 | 98 |
MAP ± SD (mmHg) | 84 ± 14 | 87 ± 11 | 73 ± 14 | 82 ± 14 | 83 ± 11 | 76 ± 9 | 78 ± 11 | 85 ± 7 | 82 ± 12 | 85 ± 8 | 79 ± 12 |
Control | 69 | 80 | 73 | 90 | 105 | 97 | 100 | 97 | 94 | 93 | 102 |
MPAP ± SD (mmHg) | 21 ± 3 | 22 ± 4 | 20 ± 3 | 19 ± 3 | 20 ± 3 | 19 ± 3 | 19 ± 4 | 20 ± 7 | 22 ± 4 | 21 ± 7 | 23 ± 5 |
Control | 21 | 23 | 21 | 20 | 20 | 20 | 18 | 18 | 16 | 18 | 18 |
CVP ± SD (mmHg) | 8 ± 2 | 11 ± 6 | 11 ± 7 | 9 ± 1 | 9 ± 3 | 8 ± 4 | 8 ± 3 | 9 ± 4 | 9 ± 4 | 7 ± 4 | 9 ± 8 |
Control | 6 | 6 | 9 | 8 | 11 | 10 | 10 | 7 | 7 | 7 | 7 |
Temp ± SD © | 38.6 ± 1.1 | 39.9 ± 2.3 | 40.8 ± 2.4 | 40.0 ± 2.1 | 39.6 ± 1.5 | 40.0 ± 1.4 | 40.4 ± 1.2 | 40.8 ± 0.8 | 41.3 ± 0.7 | 41.1 ± 0.6 | 40.6 ± 0.7 |
Control | 38.1 | 39.4 | 40.1 | 39.9 | 40.2 | 40.1 | 40.1 | 40.2 | 40.7 | 40.5 | 40.3 |
CI ± SD | 3.0 ± 0.8 | 3.1 ± 0.5 | 3.0 ± 0.4 | 3.5 ± 0.8 | 3.8 ± 1.6 | 3.8 ± 1.2 | 3.1 ± 1.6 | 3.8 ± 1.4 | 4.6 ± 1.7 | 4.3 ± 0.7 | 4.2 ± 0.6 |
Control | 2.4 | 3.5 | 2.8 | 4.1 | 2.4 | 2.4 | 3.7 | 3.1 | 3.1 | 4.8 | 4.3 |
Compliance ± SD | 33.6 ± 3.6 | 30.5 ± 4.5 | 27.8 ± 6.4 | 29.5 ± 5.5 | 27.8 ± 5.2 | 30.1 ± 4.8 | 26.2 ± 4.8 | 28.3 ± 5.8 | 24.1 ± 5.0 | 22.3 ± 6.7 | 20.0 ± 5.7 |
Control | 31.6 | 27.5 | 27.6 | 31.0 | 31.3 | 27.5 | 27.4 | 35.8 | 27.1 | 27.3 | 26.9 |
PaO2/FiO2 ± SD | 449 ± 44 | 435 ± 64 | 367 ± 80 | 419 ± 50 | 403 ± 35 | 414 ± 42 | 376 ± 36 | 386 ± 29 | 335 ± 58 | 389 ± 111 | 319 ± 91 |
Control | 460 | 393 | 368 | 458 | 448 | 438 | 453 | 433 | 418 | 393 | 395 |
pH ± SD | 7.47 ± 0.04 | 7.49 ± 0.04 | 7.48 ± 0.04 | 7.49 ± 0.03 | 7.47 ± 0.03 | 7.48 ± 0.04 | 7.48 ± 0.04 | 7.51 ± 0.05 | 7.50 ± 0.02 | 7.49 ± 0.04 | 7.49 ± 0.04 |
Control | 7.46 | 7.47 | 7.47 | 7.51 | 7.50 | 7.50 | 7.53 | 7.50 | 7.53 | 7.51 | 7.52 |
Hb ± SD (g/L) | 91 ± 8 | 96 ± 8 | 99 ± 28 | 89 ± 8 | 91 ± 8 | 83 ± 13 | 84 ± 10 | 84 ± 11 | 85 ± 16 | 85 ± 12 | 83 ± 9 |
Control | 91 | 96 | 94 | 72 | 85 | 85 | 83 | 83 | 78 | 66 | 55 |
Glucose ± SD | 9.2 ± 1.7 | 8.4 ± 1.0 | 7.9 ± 0.8 | 6.7 ± 2.4 | 6.7 ± 2.0 | 6.8 ± 1.6 | 7.2 ± 1.7 | 7.0 ± 2.2 | 6.4 ± 2.2 | 5.7 ± 1.9 | 5.2 ± 1.7 |
Control | 10.6 | 8.5 | 8.9 | 8.3 | 7.6 | 7.5 | 7.1 | 6.2 | 5.9 | 5.5 | 5.5 |
urine (IQR) output/h | 85 (70–200) | 160 (110–1060 | 240 (50–440) | 1060 (160–1200) | 520 (420–625) | 290 (200–760) | 610 (300–740) | 480 (410–900) | 360 (180–770) | 440 (200–515) | |
Control | 1240 | 1180 | 200 | 340 | 280 | 340 | 400 | 1460 | 820 | 240 | |
Lactate ± SD | 2.0 ± 0.5 | 1.2 ± 0.2 | 1.1 ± 0.4 | 1.0 ± 0.3 | 1.2 ± 0.7 | 1.6 ± 1.3 | 1.4 ± 0.7 | 1.3 ± 0.3 | 1.2 ± 0.3 | 1.7 ± 1.2 | 1.7 ± 1.3 |
Control | 2.1 | 0.9 | 1.0 | 0.7 | 0.8 | 0.8 | 0.6 | 0.6 | 0.6 | 0.7 | 0.8 |
Trc ± SD | 381 ± 98 | 187 ± 96 | |||||||||
Control | 339 | 288 | |||||||||
WBC ± SD | 24.1 ± 7.8 | 6.8 ± 2.0 | |||||||||
19.6 | 4.9 |