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Table 1 Demographics

From: Identifying a target group for selenium supplementation in high-risk cardiac surgery: a secondary analysis of the SUSTAIN CSX trial

 

Selenium

(n = 123)

Placebo

(n = 121)

p

Baseline characteristics

 

 Age (years)—median (IQR)

70 (60–76)

71 (64–77)

0.17

 Female/male—no. (%)

29 (24)/94 (76)

25 (21)/96 (79)

0.58

 Germany/Canada—no. (%)

93 (76)/30 (24)

92 (76)/29 (24)

0.94

 Body mass index—median (IQR)

27 (25–30)

28 (25–30)

0.95

 Charlson comorbidity index—median (IQR)

1 (0–2)

1 (0–2)

0.41

 Clinical frailty score—median (IQR)

3 (2–3)

3 (2–3)

0.34

Baseline chemistry

 

 GFR (ml/min/1.73 m2)—median (IQR)

82 (68–97)

81 (69–97)

0.85

 Creatinine (µmol/l)—median (IQR)

84 (73–101)

86 (72–103)

0.94

 Interleukin-6 (pg/ml)—median (IQR)

44 (32–49)

36 (22–62)

0.92

Operative characteristics

 

 EuroSCORE II—median (IQR)

9 (6–16)

8 (6–14)

0.45

 Elective/urgent surgery—no. (%)

96 (78)/27 (22)

97 (80) / 24 (20)

0.68

 Cardiopulmonary bypass (min)—median (IQR)

140 (113–178)

141 (102–190)

0.90

Baseline micronutrient status

 

 Selenium (µg/l)—median (IQR)

68 (55—114)

65 (52–119)

0.67

 Deficiency (< 70 µg/l)—no. (%)

64 (52)

64 (53)

0.73

 SELENOP (mg/l)—median (IQR)

4.5 (3.4–5.7)

4.7 (3.5–6.0)

0.75

 GPx3 (U/l)—median (IQR)

273 (187–299)

253 (204–289)

0.62

  1. GFR glomerular filtration rate, GPx3 glutathione peroxidase 3, IQR interquartile range, no. number of patients, SELENOP selenoprotein P