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Table 2 Patient cerebral physiology summary

From: Time spent above optimal cerebral perfusion pressure is not associated with failure to improve in outcome in traumatic brain injury

Physiologic metric

Median (IQR)

Duration of physiologic monitoring (hours)

69.60 (36.37–122.2)

Mean MAP (mmHg)

83.70 (79.22–88.15)

Mean ICP (mmHg)

9.010 (5.658–12.43)

 % Time ICP > 20 mmHg

1.172 (0.02757–5.752)

 % Time ICP > 22 mmHg

0.7295 (0–3.210)

Mean CPP (mmHg)

73.74 (69.8–79.85)

 % Time CPP < 60 mmHg

4.239 (1.246–9.532)

 % Time CPP > 70 mmHg

63.38 (45.10–77.95)

Mean PRx

0.1481 (0.03969–0.2767)

 % Time PRx > 0

65.68 (53.57–82.22)

 % Time PRx > 0.25

40.16 (28.22–57.05)

 % Time PRx > 0.35

30.12 (19.85–45.14)

Mean PAx

0.002225 (−0.1046–0.1171)

 % Time PAx > 0

50.6 (35.35–65.87)

 % Time PAx > 0.25

24.29 (13.09–38.87)

Mean RAC

−0.2222 (−0.3793 to −0.04453)

 % Time RAC > −0.10

34.43 (20.53–55.35)

 % Time RAC > −0.05

29.89 (17.95–49.42)

CPPopt–PRx

74.30 (69.29–80.02)

 % Time ΔCPPopt–PRx > 5 mmHg

24.46 (16.41–33.77)

 % Time ΔCPPopt–PRx > 10 mmHg

10.55 (6.787–19.32)

 % Time ΔCPPopt–PRx < −5 mmHg

24.20 (15.96–35.79)

 % Time ΔCPPopt–PRx < −10 mmHg

10.02 (4.775–19.14)

 % Time CPP > ULR–PRx

14.45 (7.156–22.45)

 % Time CPP < LLR–PRx

11.49 (5.594–26.58)

CPPopt–PAx

74.97 (71.64–82.50)

 % Time ΔCPPopt–PAx > 5 mmHg

21.76 (13.58–31.45)

 % Time ΔCPPopt–PAx > 10 mmHg

9.472 (4.634–17.82)

 % Time ΔCPPopt–PAx < −5 mmHg

30.15 (19.96–40.68)

 % Time ΔCPPopt–PAx < −10 mmHg

15.43 (8.104–25.25)

 % Time CPP > ULR–PAx

5.682 (2.755–12.74)

 % Time CPP < LLR–PAx

6.621 (2.447–16.77)

CPPopt–RAC

73.24 (69.48–79.30)

 % Time ΔCPPopt–RAC > 5 mmHg

25.63 (14.93–37.19)

 % Time ΔCPPopt–RAC > 10 mmHg

11.29 (6.417–20.08)

 % Time ΔCPPopt–RAC < −5 mmHg

22.57 (13.45–35.27)

 % Time ΔCPPopt–RAC < −10 mmHg

10.35 (3.166–18.27)

 % Time CPP > ULR–RAC

3.676 (1.691–8.185)

 % Time CPP < LLR–RAC

4.160 (1.058–9.772)

  1. AMP pulse amplitude of ICP, CPP cerebral perfusion pressure, CPPopt cerebral perfusion pressure optimum, ΔCPPopt CPP—CPPopt, ICP intracranial pressure, IQR interquartile range, LLR lower limit of reactivity, MAP mean arterial pressure, mmHg millimeters of mercury, PAx pulse amplitude index, PRx pressure reactivity index, RAC correlation (R) between slow-waves of AMP (A) and CPP (C), ULR upper limit of reactivity