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Table 1 Diffuse alveolar damage score

From: Pressure-support compared with pressure-controlled ventilation mitigates lung and brain injury in experimental acute ischemic stroke in rats

 

PCV-PEEP2

PSV-PEEP2

PCV-PEEP5

PSV-PEEP5

Atelectasis (0–16)

3.5 (2.0–4.5)

1.0 (0.0–1.3)

7 (4–12)#

1.0 (0.0–1.0)

Overdistension (0–16)

4.0 (3.8–4.5)

0.5 (0.0–1.0)

8.5 (4–13)#

1.0 (0.0–1.0)

Interstitial edema (0–16)

8.5 (7.0–9.8)*

2.0 (1.8–2.5)

8.5 (4–13)#

2.0 (1.8–2.0)

Hemorrhage (0–16)

4.0 (3.0–5.3)

1.0 (1.0–2.5)

5 (3–6.75)#

1.0 (1.0–1.3)

Thrombosis (0–16)

8.5 (7.5– 9.8)

2.0 (2.0–2.5)

8.5 (5.5–12)#

1.5 (1.0–2.0)

Inflammation (0–16)

4.0 (3.5.– 6.8)*

2.0 (1.0–2.0)

3.5 (2.0–4.0)#

1.0 (1.0–1.3)

Cumulative DAD (0–96)

34.0 (29.3–37.3)*

9.0 (7.0–10.3)

40.5 (35.5–50.5)#

7.0 (5.8–8.3)

  1. Cumulative DAD score representing injury from atelectasis, overdistension, interstitial edema, hemorrhage, thrombosis and inflammation. PCV, pressure-controlled ventilation; PEEP, positive end-expiratory pressure; PSV, pressure-support ventilation. Values are given as medians (interquartile ranges) of 6 animals in each group. Comparisons were done by Kruskal–Wallis test followed by Dunn’s multiple comparisons test (p < 0.05). *Versus the PSV-PEEP2 group; #versus the PSV-PEEP5 group