Fig. 1From: Metabolic disturbances potentially attributable to clogging during continuous renal replacement therapyMechanism of clogging. Representation of a patent hemodialysis filter A with clearance up to 60% of calcium–citrate complexes. B Occurrence of clogging leads throughout formation of an impermeable secondary membrane to an impairment of clearance capacity of the filter with consecutive rise of sodium, bicarbonate and calcium in the patientBack to article page