HS-GC–MS analysis of volatile organic compounds after hyperoxia-induced oxidative stress: a validation study

Intensive Care Medicine Experimental

Table 1 Association of VOCs linked to oxidative stress with hyperoxia exposure in patients

VOC log10 (intensity)	OR (95% CI)^a	P value	AUROCC (95% CI)^b
Hexane	1.15 (0.99 to 1.35)	0.07	0.56 (0.49 to 0.64)
Octane	1.57 (1.00 to 2.45)	0.05^c	0.60 (0.51 to 0.68)
Decane	1.20 (0.82 to 1.76)	0.35	0.48 (0.39 to 0.57)

Hyperoxia exposure was defined as a partial arterial oxygen pressure > 16.0 kPa
VOC volatile organic compound, OR odds ratio, CI confidence interval, AUROCC area under the receiver operating characteristics curve
^aPer log10 increment
^bPredictive value with hyperoxia exposure as outcome
^cRounded up