Table 3 Summary of characteristics of the obesity model
From: Sepsis and obesity: a scoping review of diet-induced obesity murine models
Authors | HFD (%kcal fat) | LFD (%kcal fat) | Time on diet (weeks) | Method of feeding | Body weighta (g; SD) | Fat massa (g; SD) | Model of obesity |
|---|---|---|---|---|---|---|---|
DeMartini [24] | 60 | 16 | 5 | Ad libitum | HFD:36.3(34.2–38.1 IQR) LFD:27.8(27.0–28.4 IQR) | HFD: 8.0 ± 2.6 LFD: 0.6 ± 0.5 | HFD |
Frydrych [25] | 60 | 13 | 22–26 | Ad libitum | NR | NR | HFD |
Gomes [26] | 19.55% lipids | 4.45% lipids | 14 | Ad libitum | HFD 25.69 ± 3.12 LFD 21.93 ± 1.57 | NR | HFD |
Goossens [27] | 45 | 10 | 12 | Ad libitum | NR | NR | HFD |
Kaplan [28] | 60 | 16 | 3 | Ad libitum | HFD: 25.2 g ± 0.4 LFD:23.4 g ± 0.4 | NR | HFD |
Kaplan. [29] | 60 | 16 | 6–7 | Ad libitum | Increasedb | Increasedb | HFD |
Khan [30] | 21% butterfat | NC | 6, 15, 27 | Ad libitum | HFD: 50.8 g ± 1.05 LFDa: 39.6 ± 1.18 | NR | WD |
Lewis [31] | 60 | 10 | 20–21 | Ad libitum | HFD: 46.6 ± 4.53 LFD: 32.3 ± 2.08 | HFD: 16.0 ± 5.21 LFD: 4.1 ± 1.30 | HFD |
Panpetch [32] | 60%w/w | 4.5% w/w | 20 | Ad libitum | Increasedb | NR | HFD |
Rivera [33] | 50 g/kg butterfat | 15 g/kg butterfat | 3 | Ad libitum | Twofold higherb | NR | WD |
Siegl [34] | 50 | 11 | 12 | Ad libitum | HFD: 34.4 ± 0.5 LFD: 27.7 ± 0.2 | NR | HFD |
Souza [35] | 60 | SC | 3 days | Ad libitum | NR | NR | HFD |
Strandberg [36] | 34.9/35.9 g% fat | 4.0/4.3 g% fat | 8 | Ad libitum | HFD: 39.3 ± 1.1 LFD 28.8 ± 0.5 | HFD: 17.0 ± 0.6 LFD: 5.5 ± 0.2 | HFD, ob/ob |
Su [37] | 60 | SC | 10 | Ad libitum | HFD: 36.5 ± 1.1 LFD: 26.4 ± 0.7 | HFD: 2.54 ± 0.09 LFD: 0.63 ± 0.02 | HFD |
Vankrunkelsven [38] | 60 kJ% | 9 kJ% | 11–12 | Ad libitum | HFD: 43.9 ± 4.7 LFD: 30.2 ± 1.9 | Increasedb | HFD, ob/ob |
Williamson [39] | 60 | 16 | 6–7 | Ad libitum | Increasedb | NR | HFD |
Yeh [40] | 60 | SC | 10 | Ad libitum | HFD: 41.5 ± 1.3 LFD: 27.7 ± 1.5 | NR | HFD |