Individualised flow-controlled ventilation reduces applied mechanical power and improves ventilation efficiency in a porcine intra-abdominal hypertension model

Intensive Care Medicine Experimental

Table 4 Lung aeration assessed with Hounsfield unit distribution from computed tomography scans at IAH grade III

lung tissue	Total^a (n = 18)	FCV^a (n = 9)	PCV^a (n = 9)	Estimate with 95% CI^b	p-value^c
Overinflated [%]	1 (1–2)	1 (1–3)	1 (0–1)	1 (0 to 2)	0.0400*
Normally-aerated [%]	81 (75–84)	84 (81–88)	76 (72–80)	8 (2 to 15)	0.0106*
Poorly-aerated [%]	11 (8–15)	7 (7–9)	15 (11–21)	− 6 (− 13 to − 3)	0.0019*
Non-aerated [%]	6 (4–8)	5 (4–6)	8 (7–10)	− 3 (− 6 to 0)	0.0315*

FCV flow-controlled ventilation, IAH intra-abdominal hypertension, PCV pressure-controlled ventilation
^aContinuous data are presented as medians (25th to 75th percentile)
^bEstimated median difference for continuous variables
^cAssessed by Wilcoxon rank sum test for continuous variables, significant differences (p < 0.05) are marked with an asterisk