Fig. 1

Time-dependent changes in MSS, body temperature, and bacterial loads in aged and young mice during the early phase of sepsis (12 h time course study). MSS (A), temperature (B), bacterial loads in PCF (C), and bacterial loads in blood (D) over time in aged and young FIP mice. Bacterial loads: aged FIP (n = 4–6/timepoint), young FIP (n = 4–6/timepoint), aged sham (n = 3/timepoint), and young sham (n = 3/timepoint). (Note: Data are presented as mean ± SD. (Note: For 1 aged FIP mouse, blood was not collected. For 1 young FIP mouse PCF and blood colonies were too confluent to count). Data are presented as mean ± SD