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Intensive Care Medicine Experimental
Fig. 1 | Intensive Care Medicine Experimental

Fig. 1

From: Isoflurane, like sepsis, decreases CYP1A2 liver enzyme activity in intensive care patients: a clinical study and network model

Fig. 1

LiMAx, lactate, INR and bilirubin of septic and non-septic patients over time (T0–T3). Grey shaded area: presence of isoflurane; box-plot using the exclusive median; x: mean; T0: before isoflurane sedation; T1, T2: with isoflurane sedation as part of routine clinical care; T3: after termination of isoflurane. a LiMAx values. Bold line indicates mean course. b Lactate. c INR. d Bilirubin. *:significant differences. LiMAx: maximum liver function capacity; INR: international normalized ratio

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