Skip to main content

Volume 3 Supplement 1


Differences between intraabdominal candidiasis in regular wards versus intensive care unit


Intraabdominal candidiasis (IAC) is a condition associated with a high morbidity and mortality in the Intensive Care Unit (ICU) [1]. Actual guidelines are centered on candidemia [2] and there are uncertainties in the diagnostic criteria for IAC, thus contributing to the scarcity of information.


Describe the characteristics of IAC in ICU patients and assess possible differences between patients with intraabdominal candidiasis in ICU compared to those in regular wards.


Retrospective multicenter, multinational study of IAC over 3 years in 13 hospitals in 5 countries. IAC was defined according to a European consensus definitions. Demographic and clinical data was recorded.


481 patients with intraabdominal candidiasis were recorded. 132 patients (27%) were at the ICU at time of diagnosis and 349 (73%) at regular wards (252 in surgical wards). There were no statistical differences in age, sex or comorbidities except for heart disease (28% ICU vs 15%ward, p= 0,002) and use of dyalisis (11%ICU vs 4% ward p= 0,005). APACHE II score was higher in ICU group (mean:18 IQR 25%-75%:14-24) vs wards (mean: 13 IQR 25%-75%:8-18) p= < 0,001.

Time from hospitalization to diagnosis was longer in ICU group (mean: 13 days IQR 25-75%: 6-30 days) compared to regular ward (mean: 11 days IQR 25-75%: 2-20 days), p = 0,006. Secondary peritonitis was the most common source of infection (39% vs 40% respectively) followed by abdominal abscess, biliary tact infection, pancreatitis and tertiary peritonitis without differences between groups. Candida albicans was the most frequent isolated strain in both groups (64% ICU vs 65%ward) follow by C glabrata, C tropicalis, C parapsilosis and C krusei with no statistical differences. Candida colonization, candidemia and septic shock were more present in the ICU population (40%,23%, and 70% respectively). Echinocandin was initiated in 43,7%, follow by azole in 21% and amphotericin B only 2,7%. Adequate antifungal treatment was more frequent in ICU population (70% versus 56%, p 0,006), adequate source control was similar in both groups (58% and 62% p 0,34) however 30 day mortality was higher in ICU patients ( 39% versus 22% p= < 0,001).


No differences in source of infection or candida species regarding ICU or regular ward were observed. Adequate initial treatment was higher in the ICU population but patients with intrabdominal candidiasis in the ICU remain as a group with high mortality probably in relation to severity of illness.


  1. Montravers P, Mira JP, Gangneux JP, et al: Clin Microbiol Infect. 2011, 17: 1061-1067. 10.1111/j.1469-0691.2010.03360.x.

    Article  PubMed  CAS  Google Scholar 

  2. Cornely OA, Bassetti M, Calandra T, et al: Clin Microbiol Infect. 2012, 18 (Suppl 7): 19-37.

    Article  PubMed  CAS  Google Scholar 

  3. Bassetti M, Marchetti M, Chakrabarti A, et al: Intensive Care Med. 2013, 39 (12): 2092-106. 10.1007/s00134-013-3109-3. Dec

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations


Rights and permissions

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lagunes, L., Borgatta, B., Antonelli, M. et al. Differences between intraabdominal candidiasis in regular wards versus intensive care unit. ICMx 3 (Suppl 1), A115 (2015).

Download citation

  • Published:

  • DOI: