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Acute effect of simultaneous discharge of TASER X26TASER X26 on anesthetized swine model
Intensive Care Medicine Experimental volume 3, Article number: A370 (2015)
Introduction
Objectives
The purpose of this study is to investigate the effects of the simultaneous discharge of TASER X26 on anesthetized swine model.
Methods
This study was a laboratory investigation approved by the animal use committee at our institute. Twelve farm-bred swine weighing between 20 kg and 25 kg were anesthetized with tiletamine/zolazepam and xylazine. The animals were exposed to TASER X26 discharge with one device or two darts (n = 5) in single group and with two devices or four darts (n = 5) in double group. The sham control group (n = 2) were studied using the same protocol as that used for animals in study groups except that they were not exposed to any TASER X26 discharges during the experiments. Hemodynamic parameters were obtained at pre-discharge, at 10, 30 and 60 minutes post-discharge. Blood parameters were obtained at pre-discharge and at 60 minutes post-discharge. Repeated-measures analysis of variance (ANOVA) was performed.
Results
The significant decrement of systolic blood pressure was shown at 10 minutes after discharge in double group. The decrement of diastolic blood pressure was shown but was not significant at 10 minutes after discharge in double group. The changes of systolic and diastolic blood pressures in double group returned to baseline by 30 minutes after discharge. In single group, the change in blood pressure was not shown. Heart rate and stroke volume index were changed but were not statistically significant in both groups. Serum S100 level, aspartate aminotransferase, and alanine tansaminase were not changed in both groups
Conclusions
Simultaneous discharge with multiple TASER X26 had an adverse effect on systolic blood pressure in anesthetized swine model.
References
Kroll MW, Lakkireddy DR, Stone JR, Luceri RM: TASER electronic control devices and cardiac arrests: coincidental or causal? Circulation. 2014, 129 (1): 93-100. Jan 7
Zipes DP: TASER electronic control devices can cause cardiac arrest in humans. Circulation. 2014, 129 (1): 101-11. 10.1161/CIRCULATIONAHA.113.005504. Jan 7
Park EJ, Choi SC, Ahn JH, Min YG: Repetitive TASER X26 discharge resulted in adverse physiologic events with a dose-response relationship related to the duration of discharge in anesthetized swine model. Journal of forensic sciences. 2013, 58 (1): 179-83. 10.1111/j.1556-4029.2012.02287.x. Jan
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Min, YG., Park, EJ. & Choi, SC. Acute effect of simultaneous discharge of TASER X26TASER X26 on anesthetized swine model. ICMx 3 (Suppl 1), A370 (2015). https://doi.org/10.1186/2197-425X-3-S1-A370
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DOI: https://doi.org/10.1186/2197-425X-3-S1-A370
Keywords
- Systolic Blood Pressure
- Diastolic Blood Pressure
- Cardiac Arrest
- Stroke Volume
- Aspartate Aminotransferase