- Poster presentation
- Open Access
Accuracy of an automatic analysis software to detect microvascular density parameters
© Carsetti et al.; 2015
- Published: 1 October 2015
- Clinical Practice
- Quality Score2
- Skilled Operator
- Wide Limit
- Automatic Software
Analysis of microvascular density parameters is time consuming and operator-dependent.1 This is the main limitation to use microvascular monitoring in clinical practice as a “point-of-care” tool. Recently, an automatic analysis software has been developed and could allow us to obtain results quickly.
The aim of this study was to assess the accuracy of microvascular density parameters (total vessel density (TVD), perfused vessel density (PVD) and proportion of perfused vessels (PPV)) obtained by the new automatic analysis software CytoCamTools 1.7.12 (CC) (Braedius, Amsterdam, The Netherlands) in comparison with Automated Vascular Analysis (AVA) software 3.2 (MicroVision Medical, Amsterdam, The Netherlands).
Sublingual microcirculatory videos were obtained using an incidence dark field-imaging device (CytoCam, Braedius, Amsterdam, The Netherlands). Only videos with a high quality score2 were selected for the analysis. Each video was analysed using AVA 3.2 by two skilled operators and results were compared with the analysis obtained by the CytoCamTools 1.7.12 software. Bland-Altman analysis was used to look at the agreement between the automatic software and the operators.
This study shows acceptable bias but wide limits of agreement for the comparison of TVD, PVD and PPV between the automated CC system and skilled operators. Further software improvements may be needed before real time point of care testing of the microcirculation can be used at the bedside.
- De Backer D, Hollenberg S, Boerma C, Goedhart P, Büchele G, Ospina-Tascon G, et al: How to evaluate the microcirculation: report of a round table conference. Crit Care. 2007, 11 (5): R101-10.1186/cc6118.PubMedPubMed CentralView ArticleGoogle Scholar
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