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Evaluation of severity in critically ill patients (cips) with limitation of life-sustaining therapy (LLST)
Intensive Care Medicine Experimental volume 3, Article number: A659 (2015)
It is considered that the severity of CIPs with LLSt is higher than the overall CIPs requiring ICU admission. The identification of specific clinical variables which determine the severity of the CIPs with LLST perhaps has not been researched enough.
To asses the severity of the CIPs with LLST in comparison to CIPs with LLS.
To evaluate and compare the mortality between two populations.
Type of study: prospective, analytical, longitudinal, and observational
Period: January 1-2011 / June 30-2014 (42 months)
Setting : Medical / Surgical ICU
Population: 2559 CIPs admitted consecutively to the ICU; sample: 220 CIPs with LLST.
Exclusión criteria: CIPs < 16 y., major burn CIPs, incomplete clinical documentation, and voluntary discharge.
Case - mix: severe sepsis, metabolic acidosis, total parenteral nutrition (TPN), oncological pathology, intra-abdominal pressure (IAP), blood products, cultures, cardiac continous output (CCO), advanced life support (ALS) before LLTS applied, FGC, FBC.
Statistical analysis: Ji squared and contrast of means (Student's t)
More than 50 % of CIPs with LLST die.
According to all clinical variables, SS, metabolic acidosis, TPN, IAP, blood products, cultures, ALS, FGC, FBC, and cardiac output are much higher in CIPs with LLST.
Wiegand DL, Grant MS: Bioethical Issues Related to Limiting Life-sustaining Therapies in the Intensive Care Unit Disclosures. J Hospice Palliative Nursing. 2014, 16 (2): 60-64. 10.1097/NJH.0000000000000049.
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Ruiz Moreno, J., González Marín, E., Esteve Paños, M. et al. Evaluation of severity in critically ill patients (cips) with limitation of life-sustaining therapy (LLST). ICMx 3, A659 (2015). https://doi.org/10.1186/2197-425X-3-S1-A659
- Public Health
- Cardiac Output
- Severe Sepsis
- Clinical Variable
- Parenteral Nutrition