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Spontaneous breathing test conducted with and without automatic tube compensation does not differ from a metabolic standpoint


Weaning from mechanical ventilation is defined as the process of release of ventilatory support and how the evaluation of this phase is conducted in the Spontaneous Breathing Test (SBT). One of the most used modes of SBT is the Continuous Positive Airway Pressure (CPAP). However, together with the mechanical ventilation modes it can be used the Automatic Tube Compensation (ATC), which compensates the resistance imposed by the endotracheal tube.


The main goal of this study was to compare the Oxygen Consumption (VO2), Carbon Dioxide Production (VCO2) and Energy Expenditure (EE) by Indirect Calorimetry (IC) during the SBT in CPAP with and without ATC.


The study was a prospective randomized, controlled crossover trial that enrolled 40 patients admitted to the Intensive Care Unit of a University Hospital. Participants were randomly allocated in Group 1, in which it was started the SBT in CPAP with ATC and later in CPAP without ATC, or in Group 2, which was started the SBT in CPAP without ATC and then CPAP with ATC.


Table 1 and graph 1 summarize the differences between the treatments ATC and without ATC concerning metabolic and respiratory variables.

Table 1


There were no metabolic differences evidenced by indirect calorimetry for VO2, EE and VCO2 during the SBT with and without ATC.

figure 1

Figure 1


  1. Dos Santos LJ, Hoff FC, Condessa RL, Kaufmann ML, Vieira SR: Energy expenditure during weaning from mechanical ventilation: Is there any difference between pressure support and T-tube?. J Crit Care. 2011, 26: 34-41. 10.1016/j.jcrc.2010.05.032.

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Lago, A., Gonçalves, E., Silva, E. et al. Spontaneous breathing test conducted with and without automatic tube compensation does not differ from a metabolic standpoint. ICMx 3 (Suppl 1), A668 (2015).

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