- Poster presentation
- Open Access
Biomarkers mesuared within 24 hours from the onset of septic shock and 28-day mortality
© de la Torre-Prados et al.; 2015
- Published: 1 October 2015
- Septic Shock
- Prospective Cohort Study
- Severity Score
- Lactate Level
Despite the remarkable advances in septic shock (SSh) management is still among the primary causes of death worldwide and there have been no significant changes in mortality over the last few decades.
Taking into account the importance of early identification and intervention in patients with SSh in relation to prognosis, we studied few biomarkers, measured within 24 hours from the onset of SSh, along with clinical score to compare their prognostic value for SSh and evaluate their The purpose of the study was to ascertain the prognostic value and evaluate their usefulness.
We conducted a prospective cohort study of 100 consecutive critically-ill adult ICU patients on first-time admission with SSh according to the Surviving Sepsis Campaign during one year. Demographic data, severity score (APACHEII and SOFA) and laboratory data were recorded. The program used for the data processing and statistical analysis was SPSS 15.0®
Distribution of biomarkers within 24 hours.
Overall population N = 100 Median (IQR)
Survivors (n = 64) Median (IQR)
Non-Survivors (n = 36) Median (IQR)
The protein MR-proADM, lactate, platelets are strongly associated with accurate assessment of the risk of mortality in SSh patients, and similar to the APACHE II and SOFA score, when measured within the first 24 hours of onset of SS.
This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.