Skip to main content

Advertisement

We're creating a new version of this page. See preview

Volume 3 Supplement 1

ESICM LIVES 2015

  • Poster presentation
  • Open Access

Primary bacteriemia and catheter related bloodstream infection in patients admitted to ICU. risk factors associated with mortality. ENVIN-HELICS registry data

  • 1,
  • 2,
  • 3,
  • 4,
  • 5,
  • 5,
  • 6,
  • 7,
  • 3,
  • 8 and
Intensive Care Medicine Experimental20153 (Suppl 1) :A889

https://doi.org/10.1186/2197-425X-3-S1-A889

  • Published:

Keywords

  • Catheter
  • Logistic Regression
  • Multivariate Analysis
  • Univariate Analysis
  • High Mortality

Introduction

Primary bacteriemia (PB) and catheter related bloodstream infections(CRBI) have been associated with higher mortality in critically ill patients.

Objectives

To study the risk factors associated with mortality in patients admitted to ICU with PB-CRBI.

Methods

Prospective, observational, multicenter and voluntary enrollment study (Spanish registry ENVIN-HELICS) [1]. All patients admitted to ICU for > 24 hours between 1st April and 30th June along the period from 2006 to 2013 were included. All episodes of PB-CRBI were recorded during the follow-up. BP-CRBI was defined according HELICS-IPSE definitions [2]. Demographic data, risk factors, ICU mortality and the presence of any non healthcare related infection were recorded. Univariate analysis was done using Chi-square test and variables found to be significant (p < 0,05) were included in a multivariate logistic regression model. p value < 0,05 was considered statistical significant.

Results

Among 129,037 patients admitted to ICU, 58,706 infections were recorded, of whom 4,479 (7.6%) were PB-CRBI. Table 1 shows risk factors found to be associated with mortality in patients with PB-CRBI in the multivariate analysis.

Table 1

Variable

Odds ratio

IC 95%

p

Age

1,01

[1,01-1,02]

< 0.05

Sex

1,06

[0,86-1,31]

NS

APACHE II

1,06

[1,05-1,08]

< 0.05

Elective surgery

0,67

[0,45-1,00]

NS

Emergency surgery

0,82

[0,60-1,11]

NS

Trauma

0,46

[0,27-0,77]

< 0.05

Continuous renal replacement

2,36

[1,87-2,98]

< 0.05

Non healthcare related infection

1,40

[1,14-1,71]

< 0.05

Conclusions

The severity of illness on admission, the use of continuous renal replacement systems, as well as the presence of non healthcare related infections, are risk factors independently associated with mortality in patients with PB-CRBI admitted to ICU.

Authors’ Affiliations

(1)
, Intensive Care Medicine, Hospital Universitari Arnau de Vilanova. IRB Lleida, Lleida, Spain
(2)
Intensive Care Medicine, Hospital Universitari Arnau de Vilanova. IRB Lleida, Lleida, Spain
(3)
Intensive Care Medicine, Hospital del Mar, Barcelona, Spain
(4)
Intensive Care Medicine, Hospital de Galdakao, Galdako, Spain
(5)
Medicina Preventiva, Hospital Universitari Vall d'Hebron, Barcelona, Spain
(6)
Intensive Care Medicine, Hospital 12 de Octubre, Madrid, Spain
(7)
Intensive Care Medicine, Hospital La Fe, Valencia, Spain
(8)
Intensive Care Medicine, Hospital de Cruces, Barakaldo, Spain

References

  1. [http://hws.vhebron.net/envin-helics/]
  2. Hospital in Europe Link for Infection Control through Surveillance (HELICS). Version 6.1. Sep. 2004. Surveillance of Nosocomial Infections in Intensive Care Units. [http://www.ecdc.europa.eu/IPSE/protocols/icu_protocol.pdf]

Copyright

© Nuvials et al.; 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Advertisement