Skip to main content


We're creating a new version of this page. See preview

Volume 3 Supplement 1


  • Poster presentation
  • Open Access

Intensive care admission in patients with hellp syndrome in a tertiary referral hospital

  • 1,
  • 2,
  • 3,
  • 4,
  • 2 and
  • 2
Intensive Care Medicine Experimental20153 (Suppl 1) :A909

  • Published:


  • Cesarean Delivery
  • Maternal Death
  • Disseminate Intravascular Coagulation
  • Eclampsia
  • Elevated Liver Enzyme


Every year, 500.000 mothers die from pregnancy-related complications, and 99% of these deaths occur in low- and middle-income countries [1]. These maternal deaths occur from complications associated with pre-eclampsia or eclampsia; hemolysis elevated liver enzymes, and low platelet (HELLP) syndrome, or other hypertensive disorder of pregnancy [2].


To identify risk factors affecting maternal outcome among women with Hemolysis, Elevated Liver Enzymes, and Low Platelets (HELLP) syndrome who required transfer for critical care.


All 77 women with HELLP syndrome who sought care for delivery and postpartum assessment at the emergency department, and who were treated in our intensive care unit between January 2007 and July 2012 were identified, retrospectively. Findings were analyzed according to surviving and non-surviving patients.


Maternal mortality rate was 14% and perinatal death occurred in 24 of 81 fetuses and newborn (30%). The most common cause of maternal complications was disseminated intravascular coagulation in 22 patients (29%), acute renal failure in 19 patients (25%), and postpartum hemorrhage in 16 patients (21%). Compared with surviving women, non-surviving women had higher mean values for international normalized ratio (p < 0.0001), levels of serum aspartate aminotransferase (p < 0.0001), serum alanine aminotransferase (p < 0.0001), lactate dehydrogenase (p < 0.0001), and bilirubin (p = 0.040) and lower platelet count (p = 0.005).


The patients with HELLP syndrome should be treated in intensive care unit, especially after cesarean delivery. Disseminated intravascular coagulation is major risk factor affecting maternal outcome.

Authors’ Affiliations

Baskent University, Ankara, Turkey
Inonu University, Malatya, Turkey
Ersin Arslan State Hospital, Gaziantep, Turkey
Malatya State Hospital, Malatya, Turkey


  1. World Health Organization: The World Health Report 2005: make every mother and child count. 2005, Geneva, World Health OrganizationView ArticleGoogle Scholar
  2. Duley L: The global impact of pre-eclampsia and eclampsia. Semin Perinatol. 2009, 33: 130-7. 10.1053/j.semperi.2009.02.010.PubMedView ArticleGoogle Scholar


© Gedik et al.; 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.