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Volume 3 Supplement 1


Prognostic factors of 30-days mortality in primary intracerebral hemorrhage


Spontaneous intracerebral hemorrhage(ICH) carries a high mortality rate and predictive factors of short-term outcome are of great importance. Studies have shown that image volumetric evaluation of hematoma, in the initial computed-tomography (CT-scan) of the brain, has an important predictive value of 30-days mortality.


To review patients (pts) with ICH, in a five-year period (January 2010-December 2014) and to assess the predictors of 30-days mortality. As the biggest diameter accounts to the calculation of the hematoma blood volume, we examined a possible association between this diameter and early fatal outcome.


Retrospective analysis of 30-days mortality in 62 pts (49 male,13 female, mean age 65,74 ± 11,18) hospitalized in our ICU. Age, Apache II score, Sofa score and GCS were recorded on admission day. CT-scan was performed in order to determine the site of the ICH, the presence of intraventricular hemorrhage (IVH) and the amount of ICH. Volume was estimated using the ABC/2 method and the biggest diameter was recorded separately. Statistical analysis was performed by using SPSS V-20 soft-ware. Variables were described using mean and SD (continues variables) or category percentages (categorical variables), stratified for survivors and nonsurvivors. Independent Samples t-test for Equality of Means, Shapiro-Wilk test of Normality, Pearson correlation and Pearson Chi-Square test were used and level of significance was set at p < 0,05.


38 pts (group I) nonsurvived in the ICU during the first month and 24 pts (group II) survived and discharged from acute hospitalization.The overall mortality was 61,29%.See results in table 1.

Table 1

Biggest diameter of hematoma and ICH volume have a positive linear correlation (Pearson correlation R2 = 0,664). Furthermore, we attempted to establish a possible association between the BD and the 30-days mortality. We divided our pts in: Group A (12 pts):BD ≤ 4 cm and Group B ( 50pts): BD > 4cm. One patient died in group A (8,3%), while 37 pts died in group B (74%) (Pearson Chi-square test p < 0,0001,odds ratio:0,032).


We demonstrated that Apache II score,Sofa score, GCS on admittion and ICH volume are independent predictive factors of 30-days mortality in pts with ICH. The size of the biggest diameter (cut off 4 cm) has a strong association with the 30-days mortality, thereby it could be an independent predictive factor in these group of patients.


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Tsikriki, S., Karathanou, A., Kokoris, I. et al. Prognostic factors of 30-days mortality in primary intracerebral hemorrhage. ICMx 3 (Suppl 1), A983 (2015).

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