Skip to main content
Intensive Care Medicine Experimental
Fig. 3 | Intensive Care Medicine Experimental

Fig. 3

From: Personalizing mechanical ventilation according to physiologic parameters to stabilize alveoli and minimize ventilator induced lung injury (VILI)

Fig. 3

Methods used to set PEEP using a combined recruitment maneuver, and PEEP titration to a PO2 + PCO2 ≥ 400. This protocol was conducted as computed tomography (CT) was being performed to measure lung volume changes. PEEP was increased to 25 cmH2O with a driving pressure (∆P) of 15 cmH2O above PEEP. If a PO2 + PCO2 ≥ 400 was not obtained, PEEP was increased by 5 cmH2O for 2 min, returned to PEEP 25 cmH2O for 2 min and repeated until PO2 + PCO2 ≥ 400 or a PEEP of 45 cmH2O was obtained. CPAP continuous positive airway pressure, OLA open lung approach [70]

Back to article page