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Intensive Care Medicine Experimental
Fig. 5 | Intensive Care Medicine Experimental

Fig. 5

From: Bradykinin receptor deficiency or antagonism do not impact the host response during gram-negative pneumonia-derived sepsis

Fig. 5

Lung cytokine and chemokine levels during pneumonia-derived sepsis in mice treated with a B1R or B2R antagonist. Indicated mediators were measured in whole lung homogenates obtained 40 h after infection from mice injected intraperitoneally with vehicle, the B1 receptor antagonist R-715, or the B2 receptor antagonist HOE-140. Data are depicted as box-and-whisker diagrams of eight mice per group at each time point. Statistical analysis was done by Kruskal-Wallis test followed by Mann-Whitney U tests where appropriate; **P < 0.01

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