Articles
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Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P88
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1071. Impact of volume resuscitation on heart rate variability in a model of hemorrhagic shock in pigs
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P87 -
1070. Effects of two different mechanical ventilation strategies on lung conditions after experimental ARDS following blunt chest trauma and pulmonary contusion in pigs
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P86 -
1069. Pharmacological preconditioning with vitamin c attenuates intestinal injury via the induction of heme oxygenase-1 after hemorrhagic shock in rats
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P85 -
0992. Effects of inhaled aerosolized insulin on acutely injured lungs under normoglycemia: insulin may contribute to enhance alveolar liquid clearance through epithelial sodium channel expression
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P77 -
0984. Perfusate from lungs ventilated ex-vivo with high tidal volumen induce in vitro endotelial dysfunction reversed by superoxide dismutase and tempol
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P69 -
0968. The influence of hypothermia and catecholamines on guinea pig's small bowel motility in vitro
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P67 -
0852. Selective decontamination of the digestive tract modulates the metabolic profile in a ventilator-induced lung injury model
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P61 -
0735. Effects of metoprolol in a porcine model of septic shock
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P57 -
0732. Sequential changes in the pattern of liver architecture in the acute phase of severe sepsis under the vision of videomicroscopy. Experimental study
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P54 -
0731. Effects of sildenafil in a porcine model of endotoxemia
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P53 -
0730. Plasma endocan levels are associated with endothelial dysfunction during experimental human endotoxemia
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P52 -
0727. Normal saline versus ringer´s lactate in experimental sepsis
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P49 -
0716. Does intravenous iron induce oxydative stress in critically ill patients? A comparison with healthy volunteers
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P47 -
0714. Interaction between adipokines and the metabolic stress response: angpt l2 cxcl5 and visfatin in patients undergoing cardiac surgery
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P46 -
0671. Extended extracorporeal lung support in a porcine acute lung injury model. Feasibility and preliminary data
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P44 -
0595. Quantitating granulocyte reactive oxygen species production by flow cytometry in a clinical setting
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P38 -
0548. Effects of sedation and muscle paralysis on inflammation during mechanical ventilation
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P32 -
0438. Effects of positive end-expiratory pressure (PEEP) on the pattern of breathing during neurally adjusted ventilatory assist. A pilot study in a mild ards porcine model
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P28 -
0918. Grey matter perfusion is preserved during normotensive hypovolaemia, despite reductions in total cerebral blood flow: evidence of local, pressure independent, intra-cerebral vascular autoregulatory response
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O26 -
0900. Effects of oxygen status on the innate immune response in humans in vivo
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O24 -
0371. Temporal changes in systemic and renal inflammation and histology in a 72-hour rat model of faecal peritonitis
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P23 -
0896. Temporal changes in tidal recruitment compared to histologic outcome in experimental acute respiratory distress syndrome
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O22 -
0356. Effect of the neuroprotective p53-inhibitor pifithrin-µ in a rodent cardiac arrest model
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P22 -
0354. Effects of sodium nitroprusside in addition to therapeutic hypothermia after experimental cardiac arrest
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P20 -
0353. Do the noble gases helium and argon exert neuroprotective effects in a rodent cardiac arrest model?
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P19 -
0329. Beneficial effects of azithromycin combined with ceftazidime without activity against P. aeruginosa in a murine sepsis model of peritonitis by Pseudomonas aeruginosa
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P18 -
0474. Circulating mitochondrial dna and vitamin d in critical illness
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O16 -
0468. Cerebral effects of lateral trendelenburg vs semirecumbent position in an experimental model of ventilator-associated pneumonia
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O14 -
0101. Early and severe impairment of lactate clearance in endotoxic shock is not related to liver hypoperfusion: preliminary report
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P12 -
0042. Burn injury stabilises extracellular atp and induces microvesicle production in skin
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O11 -
0095. Transvenous vagus nerve stimulation does not modulate the innate immune response in humans in vivo during experimental endotoxemia
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):P7 -
0032. Relationship between microcirculatory alterations and venous-to-arterial carbon dioxide differences in patients with septic shock
Citation: Intensive Care Medicine Experimental 2014 2(Suppl 1):O5 -
Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock
Microcirculatory dysfunction due to excessive nitric oxide production by the inducible nitric oxide synthase (iNOS) is often seen as a motor of sepsis-related organ dysfunction. Thus, blocking iNOS may improve...
Citation: Intensive Care Medicine Experimental 2014 2:24 -
Can computer simulators accurately represent the pathophysiology of individual COPD patients?
Computer simulation models could play a key role in developing novel therapeutic strategies for patients with chronic obstructive pulmonary disease (COPD) if they can be shown to accurately represent the patho...
Citation: Intensive Care Medicine Experimental 2014 2:23 -
Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis)
Neutrophil extracellular traps (NETs) are a central player in the host response to bacteria: neutrophils release extracellular DNA (nucleosomes) and neutrophil elastase to entrap and kill bacteria. We studied ...
Citation: Intensive Care Medicine Experimental 2014 2:21 -
Early and dynamic changes in gene expression in septic shock patients: a genome-wide approach
As early and appropriate care of severe septic patients is associated with better outcome, understanding of the very first events in the disease process is needed. Pan-genomic analyses offer an interesting opp...
Citation: Intensive Care Medicine Experimental 2014 2:20 -
The receptor for advanced glycation end products in ventilator-induced lung injury
Mechanical ventilation (MV) can cause ventilator-induced lung injury (VILI). The innate immune response mediates this iatrogenic inflammatory condition. The receptor for advanced glycation end products (RAGE) ...
Citation: Intensive Care Medicine Experimental 2014 2:22 -
A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning
We set a model of brain death, donor management, and lung transplantation for studies on lung preservation and reconditioning before transplantation.
Citation: Intensive Care Medicine Experimental 2014 2:12 -
Effects of glycemic control on glucose utilization and mitochondrial respiration during resuscitated murine septic shock
This study aims to test the hypothesis whether lowering glycemia improves mitochondrial function and thereby attenuates apoptotic cell death during resuscitated murine septic shock.
Citation: Intensive Care Medicine Experimental 2014 2:19 -
Regulation of lung oxidative damage by endogenous superoxide dismutase in sepsis
The purpose of this research is to study the relationship between superoxide dismutase (SOD) and lung redox state in an animal model of sepsis.
Citation: Intensive Care Medicine Experimental 2014 2:17 -
Relevance of induced and accidental hypothermia after trauma-haemorrhage–what do we know from experimental models in pigs?
Recent experimental research has either focused on the role of accidental hypothermia as part of the lethal triad after trauma or tried to elucidate the effects of therapeutically induced hypothermia on the po...
Citation: Intensive Care Medicine Experimental 2014 2:16 -
‘Chronomics’ in ICU: circadian aspects of immune response and therapeutic perspectives in the critically ill
Complex interrelations exist between the master central clock, located in the suprachiasmatic nuclei of the hypothalamus, and several peripheral clocks, such as those found in different immune cells of the bod...
Citation: Intensive Care Medicine Experimental 2014 2:18 -
Genetic and pharmacologic inhibition of Tpl2 kinase is protective in a mouse model of ventilator-induced lung injury
Mechanical stress induced by injurious ventilation leads to pro-inflammatory cytokine production and lung injury. The extracellular-signal-regulated-kinase, ERK1/2, participates in the signaling pathways activ...
Citation: Intensive Care Medicine Experimental 2014 2:15 -
Moderately high frequency ventilation with a conventional ventilator allows reduction of tidal volume without increasing mean airway pressure
The aim of this study was to explore if positive-pressure ventilation delivered by a conventional ICU ventilator at a moderately high frequency (HFPPV) allows a safe reduction of tidal volume (VT) below 6 mL/kg i...
Citation: Intensive Care Medicine Experimental 2014 2:13 -
Statins, fibrates, thiazolidinediones and resveratrol as adjunctive therapies in sepsis: could mitochondria be a common target?
Through their pleiotropic actions, statins, fibrates, thiazolidinediones and resveratrol can target multiple mechanisms involved in sepsis. Their actions on mitochondrial function are of interest in a patholog...
Citation: Intensive Care Medicine Experimental 2014 2:9 -
Assessment of ventilation inhomogeneity during mechanical ventilation using a rapid-response oxygen sensor-based oxygen washout method
Ventilatory inhomogeneity indexes in critically ill mechanically ventilated patients could be of importance to optimize ventilator settings in order to reduce additional lung injury. The present study compared...
Citation: Intensive Care Medicine Experimental 2014 2:14 -
Reliability of the nitrogen washin-washout technique to assess end-expiratory lung volume at variable PEEP and tidal volumes
End-expiratory lung volume measurement by the nitrogen washin-washout technique (EELVWI-WO) may help titrating positive end-expiratory pressure (PEEP) during acute respiratory distress syndrome (ARDS). Validation...
Citation: Intensive Care Medicine Experimental 2014 2:10 -
The effect of vitamin C on plasma volume in the early stage of sepsis in the rat
Previous experimental studies have shown that vitamin C has several beneficial effects in sepsis and burns, such as decreased tissue oedema, improved endothelial barrier function and decreased transcapillary l...
Citation: Intensive Care Medicine Experimental 2014 2:11 -
Bis maltolato oxovanadium (BMOV) and ischemia/reperfusion-induced acute kidney injury in rats
The aim of the present study was to test the potential protective effects of the organic vanadium salt bis (maltolato) oxovanadium (BMOV; 15 mg/kg) in the context of renal ischemia/reperfusion (30 min of ische...
Citation: Intensive Care Medicine Experimental 2014 2:3
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- ISSN: 2197-425X (electronic)